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diagnosis hepatology liver differential lfts interpretation chemistry drug elevation function gastroenterology hepatitis hepatocellular idiosyncratic induced management pulmonary rvalue tests
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury ... SinaiBmoreIMRes #Liver #FunctionTest ... #Transaminitis
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Function Tests (PFTs ... Interpretation Algorithm ... #Pulmonary #FunctionTests ... #PFTs #Interpretation ... #Algorithm #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... (>1000): • DILI ... Drug-induced liver injury ... Function #Tests #LFTs ... Diagnosis #hepatology #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... induced #Liver #Injury ... gastroenterology #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Unconjugated Bili ... > 90% of Total Bili ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver Injury ... Framework: Liver Injury ... Diagnosis #hepatology #algorithm ... #Transaminitis ... #LFTs #hepatitis
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