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diagnosis hepatology differential injury lfts abnormal acute chronic dili druginduced elevated elevation fatigue hepatocellular hepatomegaly hepatorenal hrs liverenzymes liverfunctiontests management
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... #FunctionTest # ... LFTs #Elevation #Transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... for Transaminitis ... - NAFLD, Alcohol ... #Algorithm #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... Differential #Diagnosis #Causes ... #Acute #algorithm
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Diagnosis #hepatology #algorithm ... #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • NAFLD • Alcohol ... hepatitis • Drugs ... #Causes
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... cirrhosis, severe alcoholic ... hepatitis, or acute ... • Caused by splanchnic ... • Tubular function
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Tests of synthetic function ... ALT Ratios: • Alcoholic ... differential #diagnosis #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... ascites), Chronic hepatitis ... • Autoimmune hepatitis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Renal Failure • Liver ... Epstein-Barr Virus • Hepatitis ... Alcohol) • Drug ... #causes
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