50 results
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Noncardiogenic Pulmonary Edema ... Framework NCPE Pathophysiology ... of peripheral edema ... level <100 pg/ml EKG ... left ventricular function
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... anticoagulant (e.g ... : Inhibits the function ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel function ... Aldosterone Receptor Function ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Tissue edema develops ... #Differential #Pharmacology ... #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Action #nephrology #pharmacology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... Nephron: CHF, HTN, Edema ... nephrology #Effects #pathophysiology
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
if suspected (e.g ... block (+/- daily EKG ... worsening valve function ... of infection (e.g ... Endocarditis #checklist #criticalcare
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
arrhythmia: - EKG ... clinical context & EKG ... depend on renal function ... depend on renal function ... Hypokalemia #Management #CriticalCare
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
and block this function ... more antibiotic (e.g ... cephalosporin (e.g ... transpeptidase which functions ... Proteins #AMR #PBP #pharmacology
Overview of approach to brain death

Pursuing a diagnosis of brain death too early may lead to
with brain death (e.g ... with brain death (e.g ... herniation, diffuse edema ... #Diagnosis #CriticalCare