219 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH ... #FeedbackLoop #
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... • Other rare causes ... GrowthHormone #GH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GH stimulates ... adenomas are mixed GH ... level (↑Sens) - GH ... (Lanreotide) ± GH ... or refractory cases
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
Prolactin • GH ... endocrinology #causes
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
Rouleaux Flow on POCUS ... significantly, it causes ... echogenic as in this case ... for underlying cause ... Jugular #IJ #Vein #POCUS
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Cushing's Disease • GH ... endocrinology #causes
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Pituitary adenoma (GH ... Differential #Diagnosis #Causes
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... endocrinology #causes
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Headaches • Nausea