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diagnosis differential causes endocrinology management nephrology treatment hypokalemia criticalcare epilepticus neurology status alkalosis cardiology metabolic pathophysiology pediatrics potassium acromegaly adrenalmass
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... excess: - ... #FeedbackLoop #
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... excess. ... GH excess prior ... GH excess after ... GrowthHormone #GH
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
excess occurs before ... • GH stimulates ... islet cell tumor, excess ... level (↑Sens) - GH ... (Lanreotide) ± GH
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Differential Diagnosis Algorithm ... Puberty Onset • GH ... Excess • Hyperthyroidism ... Differential #Diagnosis #Algorithm
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Differential Diagnosis Algorithm ... DHEAS Estrogen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess ... Differential #Diagnosis #Algorithm
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Differential Diagnosis Algorithm ... Hypernatremia - Excess ... consciousness • No access ... Differential #Diagnosis #Algorithm
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... thirst, Lack of access ... Hypervolemic (Excess ... Diagnosis #Workup #Algorithm
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Differential Diagnosis Algorithm ... Biopsy Androgen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess ... Differential #Diagnosis #Algorithm
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
Differential Diagnosis Algorithm ... Glucocorticoid excess ... Catecholamine excess ... Mineralocorticoid excess ... Differential #Diagnosis #Algorithm
Sellar / Pituitary Mass - Differential Diagnosis Algorithm Adenoma - Primary Anterior Pituitary - Secreting
Differential Diagnosis Algorithm ... Prolactin • GH ... Differential #Diagnosis #Algorithm
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