57 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop # ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... time of onset of GH ... GH excess prior ... GH excess after ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... • GH stimulates ... level (↑Sens) - GH ... (Lanreotide) ± GH ... Endocrinology #Treatment #Pathophysiology
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Prolactin #PRL #FeedbackLoop ... endocrinology #pathophysiology
Autoimmune Gastritis - Pathophysiology

Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI Cell, CD4 ... Autoimmune #Gastritis #Pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
IL-2 Muromonab-CD3 ... #Pharmacology #Pathophysiology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Perforation) Pathophysiology ... x 10d • 1st CDI ... for recurrent CDI ... IDSA 2021 CDI
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... mnemonic #GLFTAP #pathophysiology
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
associated with CD4 ... or CD8, depending ... ImmuneResponses #immunology #pathophysiology