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lupus sle hodgkins lymphoma management oncology vasculitis agglutinin ana antibody antinuclear autoantibodies cold comparison criteria disease disorders eularacr high hyperkalemia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... 2) LOOK FOR a cause ... → Systematic screening ... #Hemolytic #Anemia ... #treatment #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Inflammatory and Autoimmune ... Diseases: • Systemic ... lupus erythematosus ... #Diagnosis #Hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... Thrombocytopenia, Autoimmune ... hemolysis • Renal ... Highly specific antibodies ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... SLE-Related Auto-Antibodies ... #signs #symptoms ... #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Diagnosis: • hemolytic ... CLL (older) • Autoimmune ... younger pts) Differential ... #anemia #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... pericardial/abd GI ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
. pylori test (GI ... symptoms/endemic ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Lymph nodes in upper ... translocation • Types: Classification ... Extranodal disease: GI ... Diagnosis of B-Symptoms ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
neuropathy - GI ... Diagnosis: Systemic ... Symptoms (Sx) in ... #diagnosis #rheumatology ... #classification
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