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differential framework hematology phosphate aki apml causes crisis differentiation disease hyperphosphatemia hypophosphatemia igg4 kidneyinjury monoclonal phenotypes related scleroderma src syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
to cold IgG • Lupus ... vascular beds-renal ... #Hematology #Monoclonal ... #Differential #Diagnosis ... #Oncology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... thromboembolism, renal ... Post-infectious GN ... , Lupus Acute Tubular ... #nephrology
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
- Differential Diagnosis ... hyperphosphatemia: paraproteinemia ... t-PA, heparin Acute ... CKD Increased Renal ... #phosphate #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
- Differential Diagnosis ... hypophosphatemia: paraproteinemia ... , acute leukemia ... FEPO4 ≥ 5% - Renal ... #phosphate #nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Rare: DAH, acute ... , Anaphylaxis, Acute ... Renal Failure ... #management #hematology ... #oncology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
pancreas, biliary, renal ... hypergammaglobulinemia, ↑ acute ... #management #phenotypes ... #workup #treatment ... #rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis: 1) Acute ... . pauci-immune GN ... #Crisis #rheumatology ... #nephrology #diagnosis ... #management
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