31 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... #SLE #systemic ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
(SLE), Sjogren's ... Syndrome (SS), ... (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... #SLE #Gastrointestinal ... signs #symptoms #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
central nervous system ... lupus erythematosus ... #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... • Scleroderma (Systemic ... Polymerase Ill • ANCA Vasculitis ... #diagnosis #associations
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #Lupus #Erythematosus ... diagnosis #rheumatology