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differential vasculitis sle systemic msk arthropathies arthropathy causes criteria cryoglobulinemia cryoglobulins dermatology disorders eularacr glomerulonephritis inflammatory jointpain monoarthritis monoarticular orthopedics
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus ... in at least 2 joints ... #Erythematosus ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Sarcoidosis • GPA ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... with Systemic Lupus ... Erythematosus ( ... should have other symptoms
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
- Differential Diagnosis ... Algorithm Monoarticular ... Arthritis • Systemic Lupus ... Erythematosus ... polyangiitis (GPA
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... ANCA (C-ANCA): GPA ... #differential #diagnosis ... #algorithm #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Arthritis: • Joint ... : • Symptoms limited ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... phenomenon (20%) Joints ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... vesicular eruption - Joints ... and branches • GCA ... #rheumatology # ... classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Elevated ESR and CRP GCA ... develop in pts with GCA ... ischemia • Skin: Erythematous ... • Progressive symptoms ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus ( ... #types #classification ... #rheumatology #
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