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differential management hematology signs erythematosus joint msk oncology systemic antibodies antinuclear approach classification disease druginduced leukemia syndrome vasculitis activation aortitis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... : The ANA patterns ... #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... - Hemolytic anemia ... and Lupus Mimickers ... autoantibodies #signs #symptoms ... #differential #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... • Immunologic Workup ... #table #rheumatology ... #diagnosis #management
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus (SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • Joint pain ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... #Rheumatology
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
Patterns Osteoarthritis ... ulnar deviation • SLE ... PsA, Sickle cell anemia ... #patterns #hand ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... • Is there a pattern ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint Pain ... or nerve root Symptoms ... #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
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