34 results
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... should have other symptoms
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
histiocytosis, and ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... (C-ANCA): GPA > ... #differential #diagnosis ... #algorithm #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... phenomenon (20%) Joints ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Diagnosis Algorithm ... HLH syndrome 5. ... #Pancytopenia #Workup ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Diagnosis Algorithm ... HLH syndrome 5 ... #Pancytopenia #Workup ... #Algorithm #Hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology ... #diagnosis #differential