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diagnosis algorithm lymphadenopathy arthritis focal localized msk vasculitis workup acronym anemia approach classification clinical comparison disorders erythematosus extravascular glomerulonephritis gout
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Metastatic) #Diffuse ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Platelet Disorders - Differential ... HCV testing - Lab ... or if a primary hematologic ... #Workup #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy - Differential ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoantibodies: • WAIHA • CAD ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Detectable HIV viral load ... Myopathy • Diffuse ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Erythematosus #Diagnosis #Rheumatology
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... of Thrombocytopenia ... Liver Disease, Lab ... #Differential # ... Diagnosis #Hematology
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