11 results
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
- Differential Diagnosis ... : • Acute GN ... • Acute/Chronic ... Vasculitis • Lupus ... #causes
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... - Differential Diagnosis ... thromboembolism, renal ... Post-infectious GN ... , Lupus Acute Tubular
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... Bleeding (64%) • Renal ... Thromboembolism (7%) • CNS ... #diagnosis #causes ... #treatment #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor and lupus ... DIC ABNORMAL ... discern these causes ... #Hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
G6PD first) DIC ... intravascular coagulation ... Treat underlying cause ... , hypotension, renal ... #HemeOnc #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Distal (Type I) renal ... Membranoproliferative GN ... • Nephrogenic DI ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... Fibrinolysis & DIC ... #Oncology #Diagnosis
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis: 1) Acute ... . pauci-immune GN ... • Refractory cases ... #Crisis #rheumatology ... #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... pain, dark urine, DIC ... , hypoTN, renal ... #Transfusion #diagnosis ... #management #hematology