11 results
diagnosis differential classification hematology syndrome anca antibodies antibody antineutrophil antinuclear aortitis bleeding bruising cryoglobulinemia cryoglobulins dermatology glomerulonephritis limping management monoclonal
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... associated vasculitis ... Arthritis (RA), Systemic ... lupus erythematosus ... Differential #Diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... often causes arthritis ... Others: • Lupus ... lupus erythematosus ... differential #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Differential #Diagnosis #Oncology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... drug-induced SLE) • Systemic ... Vasculitis: • ... antibodies #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... Presentation: Systemic ... Central Nervous System ... often causes arthritis ... Differential #Diagnosis #Rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... ASA) • Renal Disease ... Vascular System ... • Steroids • Vasculitis ... #Causes #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
NON-WEIGHT BEARING CHILD ... FLAGS - In all cases ... guidelines General - Systemic ... Rheumatology ... #Limping #NWB #Algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... lupus erythematosus ... classification #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Membranoproliferative GN ... Vasculitis: • ... Sjogrens #Syndrome #Rheumatology
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