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Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria

#Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
for Systemic Lupus ... Erythematosus - ... ACR and SLICC Criteria ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... SLE), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
using clinical and ... American College of Rheumatology ... American College of Rheumatology ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Erythematosus Clinical ... and Immunologic ... - ANA level above ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria ... Erythematosus ... low C4, Low C3 and ... #Erythematosus ... #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
M DAMN SHARP - Lupus ... Antinuclear Antibody (ANA ... Pleuritis) H Hematologic ... #erythematosus ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Shrinking lung syndrome ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Vesicopustule on erythematous ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #Systemic #Lupus ... #Erythematosus ... Summary #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... Inflammatory and ... Diseases: • Systemic lupus ... erythematosus ... Differential #Diagnosis #Hematology