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diagnosis differential management algorithm ana antibodies patterns arthritis bcell causes disease dlbcl erythematosus laboratory lad large lymphadenopathy lymphoma monoclonal nephritis
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm By Matthew Ho, MD PhD @MatthewHoMD #Diffuse
Diffuse large B ... Management and Treatment ... MatthewHoMD #Diffuse ... #Algorithm #oncology ... #hematology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... Hodgkin's Lymphoma #Diffuse ... Algorithm #Causes #Hematology ... #Oncology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... , Drug-induced Lupus ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... • Class IV - Diffuse ... glomeruli) Diffuse ... Nephritis #Management #treatment ... #management #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... Screening Tests for Diffuse ... diagnosis #testing #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Membranoproliferative GN ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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