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diagnosis ana patterns antibodies antibody testing vasculitis approach arthritis classification clues cytoplasmic erythematosus msk pain system vasculitides workup
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... scleroderma (SSc) • Nucleolar ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Scl70 (in some cases ... ARUPLabs #ANA #Antinuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... ANA) ANA or Anti-NucIear ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... #Patterns #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Like in this case ... Chronic = RA, SLE ... #rheumatology # ... approach #workup #differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... vesicular eruption • Joints ... tract, and often causes ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... vesicular eruption - Joints ... vasculitis, and SLE ... #diagnosis #rheumatology
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