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management differential druginduced erythematosus systemic neurology syndrome vasculitis activation anisocoria classification clinical cns comparison dil hematology horners macrophage medications ophthalmology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... of Lupus Cerebritis ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... life-threatening • Treatment ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... extremities Drug ... • Antihistone: Drug ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Lupus Erythematosus ... SLE High risk ... for 1 year of treatment ... #differential #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... SLE, atherosclerotic ... disease, drug reactions ... viral infection, drug ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... systemic lupus ... vasculitis, and SLE ... #rheumatology #
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
She demonstrated ... consistent with a diagnosis ... or induced by treatment ... ophthalmology #physicalexam ... #neurology #Anisocoria
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 Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment
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