21 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: Post-strep ... GN, Lupus Nephritis ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of Vasculitis ... Vasculitis of ... - Churg-Strauss ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
-C3 GN • Cast ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis and Vasculitides ... rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Causes of Pharyngitis - Differential Diagnosis
Infectious:
 • Bacterial: Group A Strep, Group B and C Strep,
Bacterial: Group A Strep ... Group B and C Strep ... Viruses Autoimmune: Lupus ... syndrome, ANCA vasculitis ... DIHS (formally DRESS
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Disease: Systemic Lupus ... Erythematous, Systemic Vasculitis ... Differential #Diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... Polymerase Ill • ANCA Vasculitis ... Autoantibodies #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Rapidly progressing GN ... • Pauci immune GN ... , pauci-immune GN ... or ulcers) • GN ... Differential #Diagnosis #Rheumatology
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
Renal: • Acute GN ... Autoimmune: • Vasculitis ... • Lupus • Polyarteritis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... ANCA-Associated Vasculitis ... Polyangiitis (Churg-Strauss ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology