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diagnosis erythematosus hematology vasculitis antibodies antinuclear management patterns symptoms activation aortitis autoantibodies behcet causes cryoglobulinemia cryoglobulins disease eularacr high hyperkalemia
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Syndrome (SS), ... (SLE), Systemic ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... #Criteria #SLE ... #Systemic #Lupus ... Erythematosus #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Diagnosis and Lupus ... #Systemic #Lupus ... autoantibodies #signs ... #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Inflammatory and ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... • Epstein-Barr virus
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Histopathologic criteria ... #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis ... #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... purpura: strong sign ... LFT • ESR • ANA ... SLE) • Urinalysis ... #classification
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