31 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology ... #diagnosis #differential
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... (RA), Systemic lupus ... erythematosus (SLE ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Juvenile Idiopathic Arthritis ... : Lupus (SLE), Systemic ... Juvenile Idiopathic Arthritis ... #patterns #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... : - ANA > ... : Chronic disease ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management ... • Immunologic Workup ... Positive in 60-80% of cases ... : Chronic disease ... #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Serositis Labs: • ANA ... Erythematosus #Diagnosis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... diagnosis #algorithm #rheumatology
Bronchiectasis: diagnosis and management 

Causes of localized -> diffuse bronchiectasis
Foreign body, Bronchial stenosis (tumor, .. ),
Bronchiectasis: diagnosis and ... Causes of localized ... RA, Sjögren, SLE ... #Differential # ... workup #algorithm
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
MIAMI Mnemonic for Differential ... venereum, primary and ... Dermatomyositis, rheumatoid arthritis ... , systemic lupus ... sarcoidosis Iatrogenic causes