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diagnosis differential vasculitis algorithm dermatology msk pain sle cardiology erythematosus hematology systemic classification mnemonic myocarditis oncology pericarditis treatment activation aortitis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... and management ... involvement - Joint ... with refractory disease ... #Vasculitis #Rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Inflammatory Joint ... Oligoarticular (1-4 joints ... • Systemic Lupus ... Sicca) Syndrome ... #Orthopedics #Causes
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... , Cogan's Syndrome ... : IgG4-Related Disease ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... , Cryoglobulinemia ... involvement: Anti-GBM Disease
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... & Cryoglobulinemic ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Sneddon-Wilkinson disease
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #dermatology #joint ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... Inflammatory, crystalline disease ... Like in this case ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... (e.g. systemic lupus ... classification #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... antiphospholipid syndrome ... S - Systemic Lupus
Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... cruzi (Chagas disease ... Churg-Strauss syndrome ... Sarcoidosis, Systemic lupus ... erythematosus, Takayasu arteritis
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