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diagnosis differential symptoms syndrome sle treatment vasculitis dermatology erythematosus systemic algorithm cardiology msk classification dermatomyositis druginduced hematology joint myocarditis neurology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... diagnosis #algorithm #rheumatology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
basement membrane disease ... hematuria • Signs ... Diagnostic of GN ... of glomerular disease ... Hematuria: • Urethritis
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... • Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... #Hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
immunodeficiency virus ... (Epstein-Barr virus ... Dermatomyositis, rheumatoid arthritis ... , systemic lupus ... sarcoidosis Iatrogenic causes
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 Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... cruzi (Chagas disease ... Inflammatory bowel disease ... Sarcoidosis, Systemic lupus ... erythematosus, Takayasu arteritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Causes of Myocarditis ... disorders: Systemic lupus ... erythematosus, rheumatoid arthritis ... more commonly cause ... #Myocarditis #Causes
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... • Epstein-Barr virus ... • Rheumatoid arthritis ... • Systemic lupus ... connective tissue disease
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