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diagnosis differential erythematosus myopathy sle systemic vasculitis workup antimda5dm approach autoimmune classification comparison dermatomyositis disease gout laboratory management monoarthritis monoarticular
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Rheumatica • Pain ... with temporal arteritis ... and/or joint aches ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Lyme), reactive arthritis ... #Joint #Pain #MSK ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... noninflammatory Signs ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... • Arthralgia/arthritis ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract: Abdominal pain ... Palpable purpura, joint ... and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... • Transverse Myelitis ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... vesicular eruption - Joints ... such as systemic lupus ... purpura: strong sign ... differential #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... level to exclude myositis ... low back pain) ... diagnosis #testing #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... pain of the joints ... (arthritis and ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
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