18 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
, Drug-induced Lupus ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Nodules • RA • Gout ... Tophi - Gout ... conditions #joint #pain ... differential #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... ANA #patterns #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... , Cogan's Syndrome ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... Differential #Diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Crystal induced (Gout ... - Autoimmune Rheumatologic ... fever • Lyme • Gout ... • Hepatitis B virus ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint pain ... Chikungunya - Herpes virus ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... Osteochondroma Hematologic
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... Demyelinating syndromes ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... • Fever is the main ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Joint pain • Swan ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology