15 results
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... ), ANCA associated ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Summary • Epidemiology ... life-threatening • Treatment ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
- Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease Treatment ... #rheumatology # ... management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Workup: - ANA ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... claudication, aortitis ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: SLE, Reactive ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Summary Overview ... inflammatory) • joint pain ... imaging Treatment ... #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Management Summary ... Extrapulmonary: ankle arthritis ... skin (16-32%): lupus ... presentation with fever, parotitis ... Sarcoidosis #Diagnosis #Management