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diagnosis differential erythematosus management systemic activation aortitis cryoglobulinemia cryoglobulins dermatology disease druginduced hematology joint laboratory macrophage mas myopathies myopathy myositis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Hypersensitivity vasculitis ... lesions • Discoid lupus ... dermatology #joint #pain ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... ANCA associated vasculitis ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... mucositis - Rash ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Non-autoimmune rheumatologic ... : • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... tract: Abdominal pain ... , mucositis • Rash ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... Rheumatica • Pain ... with temporal arteritis ... differential #diagnosis #comparison ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... diagnosis #types #classification ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... Petechial or purpuric rash ... SJIA], systemic lupus ... erythematosus [SLE ... #Rheumatology
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