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diagnosis differential classification sle hematology table algorithm ana antinuclear causes comparison hypersensitivity patterns reactions syndrome types activation autoantibodies criteria diffuse
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... lupus erythematosus ... #Antinuclear #Antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... ANA #patterns #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... • Arthritis domain ... Highly specific antibodies ... #Lupus #Erythematosus ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... SLE-Related Auto-Antibodies ... #Lupus #Erythematosus ... #differential #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Reactive: - Systemic ... Inflammatory • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis ... • Acne • Allergy
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... lupus erythematosus ... 1, SCL-70, RNP antibodies ... #Lupus #Erythematosus
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies ... - Local and systemic ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... erythematosus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... lupus erythematosus ... lupus erythematosus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Action: IgG/lgM antibodies ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic ... lupus erythematosus ... reactions #types #allergy
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