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differential vasculitis classification cryoglobulinemia management algorithm gammopathy oncology significance types champs clinical complement crisis cryoglobulins glomerulonephritis hypocomplementemia involvement low mgrs
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... POEMS, AL amyloid, Cryoglobulinemia ... Renal-centered ... #Differential #Diagnosis ... #hematology #oncology
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... arterioles) MONOCLONAL ... arthritis • Renal ... #Vasculitis #Diagnosis ... #Rheumatology #
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Algorithm #Lupus ... Classification #Algorithm #diagnosis ... differential #types #rheumatology ... #nephrology #renal
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... min/1.73 m2 at diagnosis ... TerrierBen #Renal ... Vasculitis #Management #Rheumatology ... #Nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
& Cryoglobulinemic ... to cold IgG • Lupus ... vascular beds-renal ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... , Cryoglobulinemia ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... S - Systemic Lupus ... Erythematosus (total 50, renal ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Composed of monoclonal ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... pulmonary and renal ... such as systemic lupus ... • Urinalysis (Renal ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... Vasculitis Differential Diagnosis ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
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