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diagnosis symptoms causes hematology cardiology erythematosus sle algorithm ana antibodies antinuclear myocarditis patterns pericarditis vasculitis activation acute aortitis arthritis associations
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... • Epstein-Barr virus ... #Diagnosis #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... , Cogan's Syndrome ... (RA), Systemic ... lupus erythematosus ... #Diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... RA: rheumatoid arthritis ... lupus. ... CTILD #Diagnosis #Differential ... Table #Pulmonary #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Neutropenia - Differential ... • Epstein-Barr Virus ... Destruction • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis
Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Churg-Strauss syndrome ... , Sarcoidosis, Systemic ... lupus erythematosus ... , Takayasu arteritis ... #Myocarditis #differential
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