24 results
diagnosis differential dermatology management secondary thrombocytosis hyperpigmentation nephrology oncology rheumatology skin systemic alkaline alp aplastic approach b12 cerebritis chronic ckd
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • B12/Folate Deficiency ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... specifically: iron deficiency ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... necrosis) • VIT K deficiency ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Spoon-shaped • Iron deficiency ... • Nephrotic syndrome ... Differential #Diagnosis #Algorithm ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Pulmonary Disease Neurologic ... • Somatization Disorder ... Chronic Fatigue Syndrome
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Kawasaki, Nephrotic syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... lymphoproliferative disorders ... G6PD deficiency) ... differential #diagnosis #hematology ... #anemia
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