16 results
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Dysfunction, Weight gain ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine Deficiency ... thiamine (vitamin B1) deficiency ... ataxia (broad-based gait ... and retrograde amnesia ... #B1 #thiamine #deficiency
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
- Anterograde amnesia ... Benzodiazepines #Psychiatry ... #Pharmacology #pathophysiology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... • Persons with psychiatric ... breath, wasting, anemia ... Psychiatric symptoms ... Loss of teeth Anemia
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
pruritus, weight gain ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• Vitamin C deficiency ... • Pernicious anemia ... /B12 deficiency ... collection with EDTA Pathophysiology ... ) - Waddling gait
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... Worsening macrocytic anemia ... wt loss • If anemia ... parasthesias, gait ... B12 #Cobalamin #Deficiency
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
/pleasure) - Anergia ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
The underlying pathophysiology ... of the baseline anaemia ... co-existent G6PD deficiency
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... • Severe iron deficiency ... anemia (reduced ... Differential #Diagnosis #Pathophysiology