21 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... tolerance • Weight gain ... signs #symptoms #endocrinology ... #pathophysiology
Hirsutism - Differential Diagnosis
Defined as excessive dark, coarse, male-pattern hair growth
Hirsutism causes in premenopausal women:
 •
Hirsutism - Differential ... Cushing's Syndrome, Acromegaly ... Cushing's Syndrome, Acromegaly ... mendesthiagob #Hirsutism #Differential ... #Diagnosis #endocrinology
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Pituitary path • Acromegaly ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Differential Diagnosis ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Hyperphosphatemia - Differential ... Pseudo-hypoparathyroidism • Acromegaly ... HighPhosphate #Differential ... Diagnosis #Algorithm #endocrinology
Hyperglycemia - Differential Diagnosis Algorithm
Diabetes Mellitus:
 • Impaired Glucose Tolerance
 • Type I Diabetes
 • Type
Hyperglycemia - Differential ... Cushing's Syndrome • Acromegaly ... #HighGlucose #Differential ... Diagnosis #Algorithm #endocrinology
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Hypogonadism • Acromegaly ... disease - Weight gain ... Symptoms #Diagnosis #Endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Toxicities: Weight gain ... Sulfonylureas #Pharmacology ... DM2 #diabetes #endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
#Medications #pharmacology ... #pathophysiology ... #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology