8 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... the pituitary gland ... #Symptoms #Diagnosis ... #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... Overproduction #diagnosis ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Differential Diagnosis ... #Endocrinology ... #Treatment #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... - Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... Growth Hormone (GH ... evaluate pituitary gland ... Testing #Algorithm #diagnosis ... #endocrinology
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
- Differential Diagnosis ... Puberty Onset • GH ... Resistance • Acromegaly ... #Differential #Diagnosis ... #Algorithm #endocrinology
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
- Differential Diagnosis ... Prolactin • GH ... Autoimmune • Giant ... #Differential #Diagnosis ... #Algorithm #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
thyroglobulin, Thyroid gland ... Dysphagia, Thyroid gland ... GravesDisease #pathophysiology ... #endocin #endocrinology ... symptoms #signs #diagnosis