864 results
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
High Thrombin Generation ... Clot #Cirrhosis #Pathophysiology
Aphasia - Pathophysiology and Clinical Findings
Broca's Aphasia - Expressive language impairment: non-Fluent
 - Sensory speech areas
Aphasia - Pathophysiology ... Area → ↓output or generation ... deficits #Aphasia #Pathophysiology
Schistosoma Life Cycle - Schistosomiasis
1) Eggs shed from infected human: in feces, in urine
2) Eggs hatch
snail (successive generations ... lose tails during penetration ... Schistosomiasis #diagnosis #pathophysiology
Cephalosporin Antibiotic Generations - Mnemonic
1st Generation "FA/PHA": CEFAZOLIN, CEFADROXIL, CEPHALEXIN, CEPHALOTHIN, CEPHAPIRIN, CEPHRADINE
2nd Generation "Everything Else":
Cephalosporin Antibiotic Generations ... - Mnemonic 1st Generation ... CEPHRADINE 2nd Generation ... CEFUROXIME 3rd Generation ... MOXALACTAM 4th Generation
Cephalosporin Comparison - Coverage 
1st Generation Cefazolin, Cephalexin 
2nd Generation Cefaclor, Cefotetan, Cefoxitin, Cefuroxime 
3rd Generation
Coverage 1st Generation ... Cephalexin 2nd Generation ... Cefuroxime 3rd Generation ... " or "advanced generation ... Similar to 3rd generation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
complexes with FVIIa generating ... models #hematology #pathophysiology
Dupuytren’s Disease: Pathogenesis and Clinical Findings
 • Aging, smoking and/or diabetes -> Microangiopathy and palmar fascia
• Trauma -> Generation ... #Contractures #pathophysiology
Antibiotic Tissue Penetration

Blood Brain Barrier: Penicilins (IV), 3rd & 4th generation Cephalosporins (IV), Meropenem, TMP-SMX, Metronidazole,
Antibiotic Tissue Penetration ... IV), 3rd & 4th generation ... Poor Abscess Penetration ... Antibiotic #Tissue #Penetration
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... away from ATP generation ... respiratory #hypoxia #pathophysiology
Cephalosporins - Table of Coverage by Generation

1st Generation   Cefazolin, cephalexin 
2nd Generation Cefotetan 
3rd
of Coverage by Generation ... 1st Generation ... cephalexin 2nd Generation ... Cefotetan 3rd Generation ... Cefepime 5th Generation