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Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Class Overview Gentamicin ... . aerobic Gram negatives ... : serious gram negative ... Aminoglycosides #Gentamicin
Table of Antibiotics for Highly Resistant Gram Negative Infections 

Ceftazidime, Cefepime, Piperacillin/ Tazobactam, Carbapenems, Aztreonam, Aminoglycosides
Resistant Gram Negative ... Aminoglycosides (Gentamicin
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture Negative ... as a cause of a negative ... Neisseria gonorrhoeae, bartonella ... - Fastidious: Bartonella ... - Fastidious: Bartonella
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... for Coxiella, Bartonella ... , Bartonella). ... #BloodCulture #Negative
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Endocarditis (IE) Has Negative ... cause of culture negative ... C. burnetii , Bartonella ... #Endocarditis #Negative
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
FP + TN) = true negatives ... all positives Negative ... FN + TN) = true negatives ... / all negatives ... Specificity) Negative
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... endocarditis Bartonella ... causes #culture #negative
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
disease caused by Bartonella ... bacilliformis: - Gram negative ... diagnosis #management #Bartonella
Doxycycline - Coverage and Indications
 • Staphylococci (S aureus + CoNS)
 • The tick stuff: Borrelia
agents): Brucella, Bartonella ... • Acne • Gram-negative
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
Endocarditis Native ... epidermidis - Gram-negative ... ) - Culture negative ... Enterococci - Gram-negative ... streptococci - Culture negative