9 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... circulation - Infections ... anemia • ... Acute HTR - Mechanical ... #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... drug induced • Infections ... #Anemia #Differential ... #classification ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Inflammation, Chronic Infection ... #MCV #Classification ... #Hematology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... production (eg, hemolytic ... anemias, hemolytic ... #unconjugated #differential ... #causes
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... Thrombocytosis): • Acute ... infection • Solid ... malignancies • Anemia ... iron deficiency, hemolysis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... - APLS • Acute ... pneumoniae Vascular Fragility
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate ... #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • Viral infections ... (acute HIV, HBV ... Thalassemia, Sickle cell anemia ... inflammation (acute ... #ProteinGap #differential
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... leukocytosis, in vitro hemolysis ... #Hyperkalemia #Differential ... High #Potassium #Classification ... #Causes