635 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Localization #Nephron #Defects
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Epithelial #Inherited #Defects
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
syndromes - Gitelman ... - Genetic defects
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
nephrocalcinosis (FHHNC) • Gitelman's ... ab • Genetics defects
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
tubule reabsorptive defect ... furosemide-like lesion) • Gitelman
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... krithicism #Gitelman
Clinical features of focal cortical brain lesions in a right-handed individual

Frontal, either:  
Intellectual impairment, 
Personality
Homonymous field defect ... Homonymous field defect ... Homonymous field defect ... Visual field defects ... Visuospatial defects
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman ... dr_missyhanna #Gitelman
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
• H secretion defect ... Carbonic anhydrase II defects ... • H gradient defect ... problem • Voltage defect ... NH3 secretion defects
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Isocoria - Pupillary Defects ... Afferent Pupil Defect ... Pupillary #Pupils #Defects