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differential nephrology aki hematuria complications microscopy rheumatology syndromes urology vasculitis algorithm ankylosingspondylitis atlas blood glomerulonephritis hyperuricemia key locations management manifestations
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Diseases #Nephritic
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... disease, but can ... glomerular disease ... renal disease
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Acute #Kidney #
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... disease - Post-infectious ... Tubulointerstitial disease ... #Kidney #Injury
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... INTRINSIC: - Glomerular ... tubular cell casts ... or pigmented casts ... #Kidney #Injury
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... RBCs and/or RBC casts ... epithelial side of glomerular ... • Thin GBM disease ... • Pauci-immune disease
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... basement membrane disease ... : - RBC casts ... disease Renal
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... Disease Associations ... breakdown of cellular casts ... heme-granular casts ... disease Red blood
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Causes of Hematuria ... Renal: - Glomerular ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... (Dense deposit disease ... #renal
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