12 results
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... immune deposits in glomeruli ... post-infectious GN Anti-Glomerular ... Diagnosis #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... epithelial side of glomerular ... • Thin GBM disease ... endothelial side of glomerular ... • Pauci-immune disease
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... A small vessel vasculitis ... directed against the glomerular ... #GIomeruIar #Basement ... #nephrology #pulmonary
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... disease - Post-infectious ... #diagnosis #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Diagnosis for Pulmonary ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... sclerosis • Anti-Glomerular ... #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
(MPGN) AKA: Mesangiocapillary ... formation along glomerular ... (Dense deposit disease ... #MPGN #nephrology ... #diagnosis #renal
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... • Limited to Kidney ... : Anti-GBM Glomerulonephritis ... Disease (Goodpasture's ... #Vasculitis #differential
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... impairment), heart disease ... cluster, the diseases ... #diagnosis #glomerular
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... • Causes of Glomerular ... • Signs of glomerular ... of GN or vasculitis ... Suggestive of glomerular
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Skin, glomeruli ... (anti-C1q Vasculitis ... : glomerular ischemia ... Kidneys -> glomerulonephritis ... differential #diagnosis