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differential nephrology algorithm hematuria urology acute aki injury management blood erythematosus hypertension indications lupus membranoproliferative mpgn nephritic nonglomerular progressive prs
Causes of Hematuria - Glomerular vs Non-glomerular == Glomerular == - Glomerulonephritis - Thin basement membrane disease ==
- Glomerular vs ... Non-glomerular ... == Glomerular ... == - Glomerulonephritis ... == Non-glomerular
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- Small vessel vasculitis ... - TTP/HUS • Glomerular ... glomerulonephritis ... tubular necrosis (causes ... #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
arthritis. (± glomerulonephritis ... - Skin, glomeruli ... : glomerular ischemia ... Kidneys -> glomerulonephritis ... classification
Causes of Hematuria - Differential Diagnosis Renal: - Glomerular - IgA Nephropathy, Thin basement membrane, Alport syndrome,
Renal: - Glomerular ... syndrome, Other glomerulonephritis ... - Interstitial nephritis ... Medullary sponge kidney ... necrosis, Sickle cell disease
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... of glomerular hematuria ... Suggestive of glomerular ... disease Renal
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... • Limited to Kidney ... #diagnosis #algorithm ... #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... clinical context and signs ... • Glomerulonephritis ... / Vasculits: ANCA ... • Interstitial nephritis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... Sjogren's, rheumatoid arthritis ... (Dense deposit disease ... MPGN #nephrology #diagnosis ... #renal
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... of glomerular disease ... disorders #glomerular ... #diagnosis #glomerulonephritis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Vascular: Rheumatoid vasculitis ... Pericarditis • Renal ... Tubulo-interstitial nephritis ... amyloid, Membranous glomerulonephritis ... #diagnosis #rheumatology
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