12 results
diagnosis differential causes abnormal algorithm aptt bleeding bruising dermatology intravascular pathophysiology prolonged pt anemia arterial centralretinalartery comparison crao deficiencies dic
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
• Vasculitis Coagulation ... • Factor VIII Deficiency ... • Factor IX Deficiency ... • Vitamin K Deficiency ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... Hemophilia A - Deficiency ... EricsMedicalLectures/ #Coagulation ... comparison #diagnosis #hematology ... #deficiency
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Acquired deficiency ... Congenital intrinsic coagulation ... intravascular coagulation ... #differential #hematology ... #coagulation
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... Kasabach-Merritt syndrome Coagulation ... necrosis) • VIT K deficiency ... Differential #Diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
single factor deficiency ... severe fibrinogen deficiency ... • Congenital deficiency ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... thrombopoietin deficiency ... Intravascular #Coagulation ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
. == Deficiency ... inhibitor of a coagulation ... • Factor XIII deficiency ... intravascular coagulation ... Differential #Diagnosis #Hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Protein C & S deficiency ... , ATIII deficiency ... ) -> Increased coagulation ... decreased anti-coagulation ... • Hematologic
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... clotting factor deficiency ... ↑ → fibrinogen deficiency ... ↓ → fibrinogen deficiency ... interpretation #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... G6PD deficiency) ... differential #diagnosis #hematology
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