32 results
diagnosis differential causes hepatology algorithm anemia management hemolysis hepatitis intravascular rheumatology testing treatment aih cirrhosis coagulation dermatology extravascular hemolytic interpretation
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • B12 Deficiency ... • Folate Deficiency ... methotrexate) • Drugs Autoimmune ... CLL • APLA Alloimmune ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Hemophilia A - Deficiency ... Viral hepatitis, Autoimmune ... - Malignancy, Autoimmune ... comparison #diagnosis #hematology ... #deficiency
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Interpretation Iron deficiency ... Ferritin Iron deficiency ... Interpretation #deficiency ... #differential #hematology ... #laboratory
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... II, fibrinogen deficiency ... Thromboplastin #laboratory ... #hematology #diagnosis
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... Inflammatory and Autoimmune ... B12 • Folate deficiency ... Differential #Diagnosis #Hematology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Hepatitis - Autoimmune ... -1 antitrypsin deficiency ... #Differential #Hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
inflammation) • Iron deficiency ... - Extrinsic: Autoimmune ... Megaloblastic: Folate deficiency ... , B12 deficiency ... Differential #Diagnosis #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microspherocytes: Autoimmune ... Bite cells: G6PD deficiency ... Smear #Analysis #hematology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... 1 antitrypsin deficiency ... Presence of atypical laboratory ... SMA >1:80 #Autoimmune ... Hepatitis #Diagnosis #Hepatology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
clotting factor deficiency ... Patient has a factor deficiency ... Study #diagnosis #hematology ... pathophysiology #hematology ... #laboratory
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