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diagnosis causes dermatology abnormal algorithm aptt bleeding bruising intravascular prolonged pt rheumatology alopecia anemia arterial dic disseminated embolism erythematosus extravascular
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... • Factor VIII Deficiency ... • Factor IX Deficiency ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Interpretation Iron deficiency ... Ferritin Iron deficiency ... Interpretation #deficiency ... #diagnosis #differential ... #hematology #laboratory
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... vascular disorders, coagulation ... necrosis) • VIT K deficiency ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Acquired deficiency ... Congenital intrinsic coagulation ... intravascular coagulation ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... single factor deficiency ... severe fibrinogen deficiency ... Causes #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... venipuncture sites Laboratory ... thrombopoietin deficiency ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... - Protein S deficiency ... intravascular coagulation ... pathophysiology #hematology ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... intravascular coagulation ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Allopecia - Differential ... fungi Initial Laboratory ... • RPR • Laboratory ... loss #alopecia #Differential ... #Diagnosis #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... G6PD deficiency) ... Extravascular #Causes #differential ... #diagnosis #hematology
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