2079 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... Disease (Goodpasture's ... differential #diagnosis #algorithm
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... - Goodpasture's
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
sclerosis • Anti-Glomerular ... Basement Membrane: Goodpasture's ... Disease-specific testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... membrane: Goodpasture ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... FINDINGS: • AAV or Goodpasture's
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Differential Diagnosis Algorithm ... Erythematosus • Goodpasture's ... Differential #Diagnosis #Algorithm
Persistent UC Symptoms Despite 5-ASA Therapies
 • Assess for Drug Adherence
 • Disease Activity Assessment (bloody
Thiopurines - Anti-TNF ... - Anti-lntegrin ... - Anti-IL12 ... JAK Inhibitor Algorithm ... Treatment #Management #Algorithm
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Membrane Disease (Goodpasture's ... Diagnosis: • Anti-GBM ... @PulmPEEPs #Anti ... Membrane #Disease #Goodpastures
Main types of autoimmune encephalitis in the ICU. 
Anti-NMDAR anti-N-methyl-d-aspartate receptor, ADEM acute disseminated encephalomyelitis, Anti-GFAP
Anti-NMDAR anti-N-methyl-d-aspartate ... anti-glial fibrillary ... anti-gamma aminobutyric ... anti-gamma aminobutyric ... anti-leucine-rich
An Algorithm for the Management of Seizures

The management of active seizures is algorithmic, starting with a
An Algorithm for ... active seizures is algorithmic ... detailed in the algorithm ... progressively escalating anti-epileptic ... thame #Seizure #Algorithm
Management of Supratherapeutic INR and Complications of Anti-Coagulation #Management #Supratherapeutic #INR #Bleeding #Algorithm #Ddxof
Complications of Anti-Coagulation ... INR #Bleeding #Algorithm