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diagnosis pathophysiology differential management pulmonary testing immunology treatment allergy infectiousdiseases nephrology causes classification rheumatology algorithm disease hypersensitivity laboratory reactions types
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Membrane Disease (Goodpasture's ... Membrane #Disease #Goodpastures ... #AntiGBM #diagnosis
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
Rheumatic/lmmune: Goodpastures
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mediators: lgE - Antigen ... Form: Soluble antigen ... Form: Cell-bound antigen ... complex - Antigen ... Form: Soluble antigen
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... IgM - Cell-bound antigen ... binds to cellular antigen ... IgM - Soluble antigen ... - Antigen-antibody
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Anti-GBM Disease (Goodpasture's
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Anti-basement membrane: Goodpasture ... FINDINGS: • AAV or Goodpasture's
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Erythematosus • Goodpasture's
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Sensitization -> Antigen ... class II) process antigen ... within 5 minutes of antigen ... by 15 minutes) Antigen ... Exposure -> Antigen
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
Glomerulonephritis (Goodpasture's
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
disease Anti-GBM - Goodpasture's
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