79 results
Gout Management Algorithm

DOI: 10.1016/j.semarthrit.2020.04.010

#Gout #Management #Algorithm #rheumatology #uricacid
Gout Management ... .2020.04.010 #Gout ... #rheumatology #uricacid
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Inflammation of Gout ... inflammation #gout ... #uricacid #pathophysiology
Serum Uric Acid Levels - Primary vs Secondary Gout .Often the serum urate level is higher
Primary vs Secondary Gout ... higher than primary gout ... #Diagnosis #UricAcid ... Primary #Secondary #Gout
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... #UricAcid #Homeostasis ... #Gout #Pathophysiology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
• Alcohol #gout ... #UricAcid #Hyperuricemia
Causes of Hyperuricemia
Increased production
 • Solid-organ transplant
 • Tumor lysis syndrome
 • Rhabdomyolysis
 • Lesch Nyhan
Hyperuricemia #Causes #UricAcid ... #differential #gout
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
pathophysiology #gout ... #uricacid
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... These are CLASSIC gouty ... • Gouty tophus ... • Gout can present ... Gout is relatively
Uric Acid Crystals on Urine Microscopy

Dr. Telma Lemos @TELMALEMOS10

#UricAcid #Crystals #Urine #Microscopy #clinical #nephrology
TELMALEMOS10 #UricAcid
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... flares/year 2) Gouty ... NUIM_Chiefs #gout