5 results
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness ... -14 days): • Fever ... rash • Others: nausea ... renal + hepatic dysfunction ... hemorrhage • ARDS • Shock
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
• 49 million cases ... COMMON CAUSES + ... immunosuppression, chronic illness ... • Symptoms: Fever ... all suspected cases
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
infections, a common cause ... levels; dengue shock ... thrombocytopenia, and renal dysfunction ... African tick typhus (caused ... - Another cause
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
dengue severity classification ... days and presents fever ... acute febrile illness ... Shock or respiratory ... Shock evidenced
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... Infection #Fever ... #Causes #Hematology