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diagnosis differential management rheumatology druginduced sle antiphospholipid apls bleeding bruising comparison deficiency dermatology dil erythematosus extravascular gastroenterology glomerulonephritis hemochromatosis hemolysis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... suspicion for complement ... #Deficiency #Testing ... #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... perfringens - Complement-Mediated ... #Causes #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... 90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... - CRP: Usually normal ... Positive in 60-80% of cases ... 80% - Low complement ... Management #Summary #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Autoimmune Vasculitis (lupus ... #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... discern these causes ... fibrinogen levels, and testing ... Differential #Diagnosis #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... elevated, HFE gene testing ... including liver and hematologic ... hemochromatosis #algorithm
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... : • Lupus Anticoagulant ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... CRP - Usually normal ... 90% - Low complement ... Discontinuation of causal ... #DIL #rheumatology
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